Medicines discovery for auditory disorders: Challenges for industry

Natural Medicines for Psychotic Disorders

Patients with psychotic disorders regularly use natural medicines, although it is unclear whether these are effective and safe. The aim of this study was to provide an overview of evidence for improved outcomes by natural medicines. A systematic literature search was performed through Medline, PsycINFO, CINAHL, and Cochrane until May 2015. In 110 randomized controlled trials, evidence was found...

New Hopes and Challenges for Treatment of Neurodegenerative Disorders: Great Opportunities for Young Neuroscientists

LIPID DISORDERS The review of medicines for treating lipid disorders

Challenges for Gateway Discovery Protocols

Security gateways provide a practical and widelydeployed way to limit the flow of packets between administrative domains of an internetwork. Network layer gateways based on IPsec promise to provide a general foundation for this kind of control. While there has been progress on how to dynamically establish security associations between gateways, there is a need for discovery protocols that dynam...

Drug discovery in pharmaceutical industry: productivity challenges and trends.

Low productivity, rising R&D costs, dissipating proprietary products and dwindling pipelines are driving the pharmaceutical industry to unprecedented challenges and scrutiny. In this article I reflect on the current status of the pharmaceutical industry and reasons for continued low productivity. An emerging 'symbiotic model of innovation', that addresses underlying issues in drug failure and a...